Hormonal Biomarkers of Exertional Heat Stroke Susceptibility in Females

Hormonal Biomarkers of Exertional Heat Stroke Susceptibility in Females

Dr. LaitanoDr. Gemma Casadesus


We are thrilled to announce that members of the Sepsis and Critical Illness Research Center (SCIRC), Dr. Orlando Laitano, Principal Investigator (PI) from the Department of Applied Physiology and Kinesiology, and Dr. Gemma Casadesus, Co-Investigator (Co-I) from the Department of Pharmacology and Therapeutics, have been awarded a substantial 3-year research grant of $1.8 million by the Department of Defense (DoD). This grant will support their groundbreaking research focused on unraveling the intricate interplay of ovarian hormones in exertional heat stroke pathophysiology.

Exertional heat stroke poses a critical health concern, especially in high-stress environments and during physically demanding activities. Dr. Laitano and Dr. Casadesus, both distinguished experts in their respective fields, aim to shed light on the role of ovarian hormones in modulating the body’s response to extreme heat and the subsequent development of heat stroke.

This substantial funding from the DoD reflects the significance of their research proposal and the potential impact it holds for both military personnel and civilian populations. The findings from this study have the potential to reshape our understanding of heat-related illnesses and inform strategies to prevent and manage exertional heat stroke more effectively, particularly in women.

The research team will employ cutting-edge methodologies, innovative data analysis techniques, and multidisciplinary collaboration to delve into the complex mechanisms underlying the interaction between ovarian hormones and the body’s thermoregulatory system. The ultimate goal is to develop targeted interventions that can mitigate the risk of exertional heat stroke and improve the well-being of individuals working or engaging in physically demanding activities under challenging heat conditions.

This grant not only exemplifies the dedication and expertise of Dr. Laitano and Dr. Casadesus but also underscores the Department of Defense’s commitment to advancing scientific understanding for the betterment of human health and performance. As they embark on this groundbreaking research journey, we eagerly anticipate the insights and advancements that will emerge, potentially shaping the future of heat stroke prevention and treatment.

Please join us in congratulating Dr. Orlando Laitano and Dr. Gemma Casadesus on this remarkable achievement and wishing them every success as they embark on this important research venture. Their collaborative efforts stand as a testament to the potential of interdisciplinary research in addressing complex health challenges. Stay tuned for updates and discoveries that will undoubtedly contribute to the advancement of medical science and the well-being of individuals across the globe.