Best wishes to the SCIRC community members who submitted abstracts to the 46^th Annual Conference on Shock!

1. Title: INFECTION INDUCES ERYTHROBLASTIC ISLAND DYSFUNCTION IN MULITCOMPARTMENTAL TRAUMA

• Authors: Gillies GS, Munley JA, Kelly LS, Pons EE, Coldwell PS, Kannan KB, Bible LE, Efron PA, Mohr AM

2. Title: MONOCYTE ANISOCYTOSIS (MDW) IS INCREASED IN SURGICAL SEPSIS, IS ASSOCIATEDWITH MDSC EXPANSION, BUT DOES NOT IMPROVE PREDICTION OF ADVERSE CLINICAL OUTCOMES

• Authors: Valerie E. Polcz, Jaimar C. Rincon, Muxuan Liang, Ricardo Ungaro, Ivanna Rocha, Evan L. Barrios, Tyler J. Loftus, Shawn D. Larson, Philip A. Efron, Lyle L.Moldawer

3. Title: USING ELISPOT TO STUDY IMMUNE CELL FUNCTION IN PRECLINICAL SEPSIS MODELS

• Authors: Jacqueline Unsinger, Alexandra Dram, Sandra Meszaros, Julie Xu, Lyle L. Moldawer, Kenneth Remy, Vladimir Badovinac, Charles Caldwell, Scott Brakenridge, Isaiah Turnbull, Monty Mazer, Richard Hotchkiss, Thomas S. Griffith

4. Title: BCG INDUCES GESTATIONAL AGE-INDEPENDENT INNATE IMMUNE STIMULATION INNEONATES: A VALIDATION OF FUNCTIONAL IMMUNOLOGIC BATTERY WITH SMALL VOLUME BLOOD(SVB) SAMPLING

• Authors: Valerie E. Polcz, Jaimar C. Rincon, Evan L. Barrios, Russell Hawkins, Philip A. Efron, Lyle L. Moldawer, Shawn D. Larson

5. Title: ENDOTYPING SEPTIC AND CRITICALLY ILL PATIENTS USING ELISPOT: THE ‘SPIES’ EXPERIENCE

• Authors: Lyle L. Moldawer , Monty Mazer ,Michael D. Goodman , Patrick McGonagill , Robert Gould , Philip A. Efron ,Letitia Bible , Ivanna Rocha , Muxuan Liang , Isaiah R. Turnbull , Scott Brakenridge , Kenneth Remy , Vladimir Badovinac , Thomas S. Griffith, Richard Hotchkiss , Charles Caldwell

 6. Title: CITE-SEQ (CELLULAR INDEXING OF TRANSCRIPTOMES AND EPITOPES BY SEQUENCING) ILLUSTRATES A UNIQUE MYELODYSPLASIA AFTER SEPSIS

• Authors: Evan Barrios, MD; John Leary, MS; Valerie Polcz, MD; Jeremy Balch, MD; Jaimar Rincon, PhD, Tyler Loftus, MD; Alicia Mohr, MD; Michael Kladde, PhD; Clayton Mathews, PhD; Lyle Moldawer, PhD, Rhonda Bacher, PhD; Philip Efron, MD

  7. Title: SINGLE CELL RNA SEQUENCING REVEALS NOVEL MYELOID-DERIVED SUPPRESSOR CELLS IN CHRONIC CRITICAL ILLNESS VS RAPID RESPONDERS SUBACUTELY AFTER SEPSIS

• Authors: Evan Barrios, MD; John Leary, MS; Valerie Polcz, MD; Jeremy Balch, MD; Jaimar Rincon, PhD, Tyler Loftus, MD; Alicia Mohr, MD; Michael Kladde, PhD; Clayton Mathews, PhD; Lyle Moldawer, PhD, Rhonda Bacher, PhD; Philip Efron, MD

 8. Title: IL-7 Increases T Cell Function In Septic Patients (SPIES)

• Authors: Monty Mazer, Drew Del Toro, Philip Efron, Lyle Moldawer, Alexandra Dram, Sandra Meszaros, Michael Goodman, Charles Caldwell, Thomas S. Griffith, Robert Gould, Candace Nelson, Lucas Hale, Patrick McGonagill, Mohammad Heidarian, Elvia Silvia, Vladmir Badovinac, Scott Brackenridge, Kenneth Remy, Richard Hotchkiss

 9. Title: POSTINJURY PNEUMONIA INDUCES PERSISTENT SEX-SPECIFIC ALTERATIONS IN THE GUT MICROBIOME

• Authors: Jennifer A. Munley, MD; Lauren S. Kelly, MD; Gwoncheol Park, MS; Gwendolyn S. Gillies, MD; Erick E. Pons, BS; Kolenkode B. Kannan, PhD; Letitia E. Bible, MD; Philip A. Efron, MD; Ravinder Nagpal, PhD; Alicia M. Mohr, MD